Pub. Date : 2001 Dec 21
PMID : 11606574
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The cytoplasmic carboxyl-terminal domain of AE1, the plasma membrane chloride/bicarbonate exchanger of erythrocytes, contains a binding site for carbonic anhydrase II (CAII). | Bicarbonates | carbonic anhydrase 2 | Homo sapiens |
| 2 | The cytoplasmic carboxyl-terminal domain of AE1, the plasma membrane chloride/bicarbonate exchanger of erythrocytes, contains a binding site for carbonic anhydrase II (CAII). | Bicarbonates | carbonic anhydrase 2 | Homo sapiens |
| 3 | AE1-mediated chloride/bicarbonate exchange was reduced 50-60% by inhibition of endogenous carbonic anhydrase with acetazolamide, which indicates that CAII activity is required for full anion transport activity. | Bicarbonates | carbonic anhydrase 2 | Homo sapiens |
| 4 | The interaction of CAII with AE1 forms a transport metabolon, a membrane protein complex involved in regulation of bicarbonate metabolism and transport. | Bicarbonates | carbonic anhydrase 2 | Homo sapiens |