Title : Reactive oxygen species mediate cyclic strain-induced endothelin-1 gene expression via Ras/Raf/extracellular signal-regulated kinase pathway in endothelial cells.

Pub. Date : 2001 Oct

PMID : 11603923






1 Functional Relationships(s)
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1 Our data demonstrate that strain-induced Et-1 gene expression is modulated by ROS via Ras/Raf/ERK signaling pathway, and indicate the responsiveness of the AP-1 binding site for strain-induced Et-1 expression. Reactive Oxygen Species mitogen-activated protein kinase 1 Homo sapiens