Title : Neurotensin levels in specific brain regions and hypnotic sensitivity to ethanol and pentobarbital as a function of time after haloperidol administration in selectively bred rat lines.

Pub. Date : 2001 Nov

PMID : 11602683






5 Functional Relationships(s)
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1 Neurotensin levels in specific brain regions and hypnotic sensitivity to ethanol and pentobarbital as a function of time after haloperidol administration in selectively bred rat lines. Haloperidol neurotensin Rattus norvegicus
2 Single doses of haloperidol were administered to lines of rats [selectively bred for high and low sensitivity (HAS and LAS, respectively) to hypnotic effects of ethanol] to produce increases in neurotensin (NT) levels in brain regions. Haloperidol neurotensin Rattus norvegicus
3 Single doses of haloperidol were administered to lines of rats [selectively bred for high and low sensitivity (HAS and LAS, respectively) to hypnotic effects of ethanol] to produce increases in neurotensin (NT) levels in brain regions. Haloperidol neurotensin Rattus norvegicus
4 At 20 h after administration, haloperidol produced dose-dependent increases in NT immunoreactivity levels in nucleus accumbens (NA) and caudate putamen (CP) in both HAS and LAS lines. Haloperidol neurotensin Rattus norvegicus
5 Levels of NT in NA and CP returned to control values at 48 h after 4 mg/kg haloperidol. Haloperidol neurotensin Rattus norvegicus