Title : Down-modulation of c-myc expression by phorbol ester protects CEM T leukaemia cells from starvation-induced apoptosis: role of ornithine decarboxylase and polyamines.

Pub. Date : 2001 Oct

PMID : 11598794






1 Functional Relationships(s)
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1 Indeed starved cells undergo apoptosis in the presence of constitutively elevated c-myc expression and the phorbol ester, phorbol 12-miristate 13-acetate (PMA), which rescues cells from apoptosis, induces complete c-myc down-regulation. Tetradecanoylphorbol Acetate MYC proto-oncogene, bHLH transcription factor Homo sapiens