Pub. Date : 2001 Dec 28
PMID : 11598110
11 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | In the present work, we explored the potential role of insulin-induced H(2)O(2) generation on downstream insulin signaling using diphenyleneiodonium (DPI), an inhibitor of cellular NADPH oxidase that blocks insulin-stimulated cellular H(2)O(2) production. | diphenyleneiodonium | insulin | Homo sapiens |
2 | In the present work, we explored the potential role of insulin-induced H(2)O(2) generation on downstream insulin signaling using diphenyleneiodonium (DPI), an inhibitor of cellular NADPH oxidase that blocks insulin-stimulated cellular H(2)O(2) production. | diphenyleneiodonium | insulin | Homo sapiens |
3 | In the present work, we explored the potential role of insulin-induced H(2)O(2) generation on downstream insulin signaling using diphenyleneiodonium (DPI), an inhibitor of cellular NADPH oxidase that blocks insulin-stimulated cellular H(2)O(2) production. | diphenyleneiodonium | insulin | Homo sapiens |
4 | In the present work, we explored the potential role of insulin-induced H(2)O(2) generation on downstream insulin signaling using diphenyleneiodonium (DPI), an inhibitor of cellular NADPH oxidase that blocks insulin-stimulated cellular H(2)O(2) production. | diphenyleneiodonium | insulin | Homo sapiens |
5 | In the present work, we explored the potential role of insulin-induced H(2)O(2) generation on downstream insulin signaling using diphenyleneiodonium (DPI), an inhibitor of cellular NADPH oxidase that blocks insulin-stimulated cellular H(2)O(2) production. | diphenyleneiodonium | insulin | Homo sapiens |
6 | In the present work, we explored the potential role of insulin-induced H(2)O(2) generation on downstream insulin signaling using diphenyleneiodonium (DPI), an inhibitor of cellular NADPH oxidase that blocks insulin-stimulated cellular H(2)O(2) production. | diphenyleneiodonium | insulin | Homo sapiens |
7 | DPI completely inhibited the activation of phosphatidylinositol (PI) 3"-kinase activity by insulin and reduced the insulin-induced activation of the serine kinase Akt by up to 49%; these activities were restored when H(2)O(2) was added back to cells that had been pretreated with DPI. | diphenyleneiodonium | insulin | Homo sapiens |
8 | DPI completely inhibited the activation of phosphatidylinositol (PI) 3"-kinase activity by insulin and reduced the insulin-induced activation of the serine kinase Akt by up to 49%; these activities were restored when H(2)O(2) was added back to cells that had been pretreated with DPI. | diphenyleneiodonium | insulin | Homo sapiens |
9 | DPI completely inhibited the activation of phosphatidylinositol (PI) 3"-kinase activity by insulin and reduced the insulin-induced activation of the serine kinase Akt by up to 49%; these activities were restored when H(2)O(2) was added back to cells that had been pretreated with DPI. | diphenyleneiodonium | insulin | Homo sapiens |
10 | Preventing oxidant generation with DPI also blocked insulin-stimulated glucose uptake and GLUT4 translocation to the plasma membrane, providing further evidence for an oxidant signal in the regulation of the distal insulin-signaling cascade. | diphenyleneiodonium | insulin | Homo sapiens |
11 | Preventing oxidant generation with DPI also blocked insulin-stimulated glucose uptake and GLUT4 translocation to the plasma membrane, providing further evidence for an oxidant signal in the regulation of the distal insulin-signaling cascade. | diphenyleneiodonium | insulin | Homo sapiens |