Pub. Date : 2001 Oct 19
PMID : 11597762
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Caspase-3 activation and DNA fragmentation in primary hippocampal neurons following glutamate excitotoxicity. | Glutamic Acid | caspase 3 | Mus musculus |
| 2 | After glutamate stimulation (125 microM), the majority of neurons was dying between 12 and 24 h. The absolute number of active caspase-3 neurons increased only moderately but in relation of surviving neurons after 24 h from 8 to 36% (125 microM), to 53% (250 microM) or to 32% (500 microM). | Glutamic Acid | caspase 3 | Mus musculus |
| 3 | In our system, glutamate-mediated excitotoxicity effects the DNA fragmentation and caspase-3 activation. | Glutamic Acid | caspase 3 | Mus musculus |