Title : Induction of ser15 and lys382 modifications of p53 by blockage of transcription elongation.

Pub. Date : 2001 Sep 20

PMID : 11593403






1 Functional Relationships(s)
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1 In contrast, agents that inhibit the elongation phase of transcription, such as UV light, camptothecin or actinomycin D, induced the accumulation of nuclear p53 proteins that were modified at both of these sites. Camptothecin tumor protein p53 Homo sapiens