Title : Angiotensin converting enzyme gene polymorphism predicts blood pressure response to angiotensin II receptor type 1 antagonist treatment in hypertensive patients.

Pub. Date : 2001 Oct

PMID : 11593098






2 Functional Relationships(s)
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1 In the irbesartan group, individuals homozygous for the ACE gene I allele showed a greater reduction in diastolic blood pressure, exceeding those with the D allele (-18 +/- 11 SD versus -7 +/- 10 mmHg, P = 0.0096). Irbesartan angiotensin I converting enzyme Homo sapiens
2 CONCLUSIONS: ACE genotyping predicted the blood pressure-lowering response to antihypertensive treatment with irbesartan but not atenolol. Irbesartan angiotensin I converting enzyme Homo sapiens