Title : APAF1 is a key transcriptional target for p53 in the regulation of neuronal cell death.

Pub. Date : 2001 Oct 15

PMID : 11591730






3 Functional Relationships(s)
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1 Induction of neuronal cell death by camptothecin, a DNA-damaging agent that functions through a p53-dependent mechanism, resulted in increased Apaf1 mRNA in p53-positive, but not p53-deficient neurons. Camptothecin tumor protein p53 Homo sapiens
2 Induction of neuronal cell death by camptothecin, a DNA-damaging agent that functions through a p53-dependent mechanism, resulted in increased Apaf1 mRNA in p53-positive, but not p53-deficient neurons. Camptothecin tumor protein p53 Homo sapiens
3 Induction of neuronal cell death by camptothecin, a DNA-damaging agent that functions through a p53-dependent mechanism, resulted in increased Apaf1 mRNA in p53-positive, but not p53-deficient neurons. Camptothecin tumor protein p53 Homo sapiens