Title : Peroxisome proliferator-activated receptor gamma inhibits transforming growth factor beta-induced connective tissue growth factor expression in human aortic smooth muscle cells by interfering with Smad3.

Pub. Date : 2001 Dec 7

PMID : 11590167






1 Functional Relationships(s)
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1 In this study, we demonstrate that the PPAR gamma natural ligand (15-deoxyprostaglandin J(2)) and a synthetic ligand (GW7845) significantly inhibit TGF-beta-induced CTGF production in a dose-dependent manner in HASMCs. hasmcs peroxisome proliferator activated receptor gamma Homo sapiens