Title : Gene induction by Phenobarbital: an update on an old question that receives key novel answers.

Pub. Date : 2001 Sep

PMID : 11589781






1 Functional Relationships(s)
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1 The response of mammalian CYP2B genes to phenobarbital was abolished in the liver of mice carrying a null allele of the constitutive androstane receptor gene, whereas that of CYP3A genes was lost in pregnane X receptor knock-out mice. Phenobarbital cytochrome P450, family 3, subfamily a, polypeptide 11 Mus musculus