Title : The interaction of divalent copper and the microsomal electron transport system. A re-examination of the effects of copper chelates on the function of cytochrome P-450.

Pub. Date : 1979 Dec 10

PMID : 115873






1 Functional Relationships(s)
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1 In particular, it was found that the reported inhibition of cytochrome P-450-catalyzed hydroxylation reactions by copper-tyrosine is associated with an inhibition rather than a stimulation of the formation of hydrogen peroxide, the product of the dismutation of the superoxide radicals generated as a result of the decay of oxycytochrome P-450. Superoxides cytochrome P450 family 4 subfamily F member 3 Homo sapiens