Title : Vanilloid receptor ligands: hopes and realities for the future.

Pub. Date : 2001

PMID : 11587243






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 These neurons carry receptors that bind capsaicin, recently identified as the vanilloid VR1 receptor. Capsaicin transient receptor potential cation channel subfamily V member 1 Homo sapiens
2 The discovery of VR1-expressing cells in the brain as well as in non-neural tissues such as the kidney and urothelium places VR1 in a much broader perspective than peripheral pain perception, and is hoped to identify further, yet unsuspected, indications for vanilloid therapy. Capsaicin transient receptor potential cation channel subfamily V member 1 Homo sapiens
3 The realisation that VR1 and cannabinoid CB1 receptors have overlapping ligand recognition properties may also have far-reaching implications for vanilloid therapy. Capsaicin transient receptor potential cation channel subfamily V member 1 Homo sapiens