Title : Treatment of the elderly with 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors: focus on drug interactions.

Pub. Date : 2001 Jul

PMID : 11584328






1 Functional Relationships(s)
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1 Several drugs have been shown to significantly inhibit the CYP3A4 pathway; in combination with statins such as lovastatin, simvastatin, atorvastatin, and cerivastatin, they have been shown to elevate serum concentrations of these statins, or may increase the risk of myopathy. Simvastatin cytochrome P450 family 3 subfamily A member 4 Homo sapiens