Title : TPA-activated transcription of the human MnSOD gene: role of transcription factors Sp-1 and Egr-1.

Pub. Date : 2001 Aug

PMID : 11560779






1 Functional Relationships(s)
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1 The contributions of these binding sites and the roles of the transcription factors Egr-1, AP-2, and Sp1 in the activation of hMnSOD transcription by TPA were investigated by site-directed mutation analysis, Western blotting, and overexpression of transcription factors. Tetradecanoylphorbol Acetate transcription factor AP-2 alpha Homo sapiens