Title : Differential protection with inhibitors of caspase-8 and caspase-3 in murine models of tumor necrosis factor and Fas receptor-mediated hepatocellular apoptosis.

Pub. Date : 2001 Sep 15

PMID : 11559023






1 Functional Relationships(s)
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1 We conclude that Fas may rely exclusively on caspase-8 activation and mitochondria to activate caspase-3, which can process more procaspase-8 and thus propagate the amplification of the apoptotic signal. ammonium ferrous sulfate caspase 3 Mus musculus