Title : Cyclooxygenase-2, malondialdehyde and pyrimidopurinone adducts of deoxyguanosine in human colon cells.

Pub. Date : 2001 Sep

PMID : 11532880






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Activity of one of the COX isoforms, COX-2, results in production of prostaglandin E(2) (PGE(2)) via the endoperoxide PGH(2). Prostaglandins E mitochondrially encoded cytochrome c oxidase II Homo sapiens
2 Selective inhibition of COX-2 activity in HCA-7 cells by NS-398 significantly inhibited PGE(2) production, but altered neither MDA nor M(1)G levels. Prostaglandins E mitochondrially encoded cytochrome c oxidase II Homo sapiens