Title : Conservation of signaling pathways of xenobiotic-sensing orphan nuclear receptors, chicken xenobiotic receptor, constitutive androstane receptor, and pregnane X receptor, from birds to humans.

Pub. Date : 2001 Sep

PMID : 11518807






2 Functional Relationships(s)
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1 Thus, the phenobarbital-inducible enhancer units of the mouse Cyp2b10, rat CYP2B2, and human CYP2B6 genes were activated in reporter gene assays by the same compounds that activate the chicken CYP2H1 phenobarbital-inducible enhancer units. Phenobarbital cytochrome P450, family 2, subfamily b, polypeptide 2 Rattus norvegicus
2 Thus, the phenobarbital-inducible enhancer units of the mouse Cyp2b10, rat CYP2B2, and human CYP2B6 genes were activated in reporter gene assays by the same compounds that activate the chicken CYP2H1 phenobarbital-inducible enhancer units. Phenobarbital cytochrome P450, family 2, subfamily b, polypeptide 2 Rattus norvegicus