Title : Activities of monomeric insulin analogs at position A8 are uncorrelated with their thermodynamic stabilities.

Pub. Date : 2001 Oct 26

PMID : 11517220






1 Functional Relationships(s)
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1 Previous studies have demonstrated that the potency and thermodynamic stability of human insulin are enhanced in concert by substitution of Thr(A8) by arginine or histidine. Threonine insulin Homo sapiens