Title : Crystal structure of human type III 3alpha-hydroxysteroid dehydrogenase/bile acid binding protein complexed with NADP(+) and ursodeoxycholate.

Pub. Date : 2001 Aug 28

PMID : 11513593






1 Functional Relationships(s)
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1 More interestingly, the orientation of ursodeoxycholate is essentially "backwards" and "upside-down" from that observed for testosterone in the related rat 3alpha-HSD.NADP(+).testosterone ternary complex, where testosterone assumes the position of a 3-ketosteroid substrate. NADP aldo-keto reductase family 1 member C4 Homo sapiens