Title : Crystal structure of human type III 3alpha-hydroxysteroid dehydrogenase/bile acid binding protein complexed with NADP(+) and ursodeoxycholate.

Pub. Date : 2001 Aug 28

PMID : 11513593






2 Functional Relationships(s)
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Protein Name
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1 The crystal structure of human type III 3alpha-hydroxysteroid dehydrogenase (HSD)/bile acid binding protein (AKR1C2) complexed with NADP(+) and 3alpha,7beta-dihydroxy-5beta-cholanic acid (ursodeoxycholate) at 3.0 A resolution is presented. NADP aldo-keto reductase family 1 member C2 Homo sapiens
2 Like other members of the superfamily, AKR1C2 folds into an alpha/beta-barrel and binds NADP(+) in an extended conformation. NADP aldo-keto reductase family 1 member C2 Homo sapiens