Title : Effects of cruciferous vegetables and their constituents on drug metabolizing enzymes involved in the bioactivation of DNA-reactive dietary carcinogens.

Pub. Date : 2001 Sep 1

PMID : 11506821






1 Functional Relationships(s)
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1 Earlier in vivo experiments with rodents indicated that indoles and isothiocyanates, two major groups of glucosinolate breakdown products, attenuate the effects of polycyclic aromatic hydrocarbons (PAHs) and nitrosamines via induction of GST and inhibition of cytochrome-P450 isoenzymes, respectively. Isothiocyanates cytochrome P450 family 4 subfamily F member 3 Homo sapiens