Pub. Date : 2001 Aug
PMID : 11496238
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Effect of desloratadine and loratadine on rhinovirus-induced intercellular adhesion molecule 1 upregulation and promoter activation in respiratory epithelial cells. | Loratadine | intercellular adhesion molecule 1 | Homo sapiens |
| 2 | OBJECTIVE: We have investigated the effects of desloratadine and loratadine on rhinovirus-induced ICAM-1 expression, mRNA upregulation, and promoter activation. | Loratadine | intercellular adhesion molecule 1 | Homo sapiens |
| 3 | RESULTS: Desloratadine and loratadine (0.1-10 micromol/L) inhibited rhinovirus-induced ICAM-1 upregulation in both primary bronchial or transformed (A549) respiratory epithelial cells. | Loratadine | intercellular adhesion molecule 1 | Homo sapiens |
| 4 | Desloratadine and loratadine also inhibited ICAM-1 mRNA induction caused by rhinovirus infection in a dose-dependent manner, and they completely inhibited rhinovirus-induced ICAM-1 promoter activation. | Loratadine | intercellular adhesion molecule 1 | Homo sapiens |
| 5 | Desloratadine and loratadine also inhibited ICAM-1 mRNA induction caused by rhinovirus infection in a dose-dependent manner, and they completely inhibited rhinovirus-induced ICAM-1 promoter activation. | Loratadine | intercellular adhesion molecule 1 | Homo sapiens |