Title : Does aspirin attenuate the effect of angiotensin-converting enzyme inhibitors in hypertension or heart failure?

Pub. Date : 2001 Sep

PMID : 11496056






1 Functional Relationships(s)
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1 An interaction is biologically plausible, because there is considerable evidence that angiotensin-converting enzyme inhibitors exert important effects through increasing the production of vasodilator prostaglandins, whereas aspirin blocks their production through inhibition of cyclooxygenase, even at low doses. Prostaglandins angiotensin I converting enzyme Homo sapiens