Title : Design, synthesis, and structure-activity relationships of a series of 3-[2-(1-benzylpiperidin-4-yl)ethylamino]pyridazine derivatives as acetylcholinesterase inhibitors.

Pub. Date : 2001 Aug 16

PMID : 11495583






1 Functional Relationships(s)
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1 Starting from the 3-[2-(1-benzylpiperidin-4-yl)ethylamino]-6-phenylpyridazine 1, we performed the design, the synthesis, and the structure-activity relationships of a series of pyridazine analogues acting as AChE inhibitors. 3-(2-(1-benzylpiperidin-4-yl)ethylamino)-6-phenylpyridazine acetylcholinesterase (Cartwright blood group) Homo sapiens