Title : Regulation of Cbl phosphorylation by the Abl tyrosine kinase and the Nck SH2/SH3 adaptor.

Pub. Date : 2001 Jul 5

PMID : 11494134






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The major proline-rich region of Cbl was required for its phosphorylation by c-Abl, but not by a constitutively activated Abl mutant, suggesting Cbl activates c-Abl by engaging its SH3 domain. Proline Cbl proto-oncogene Homo sapiens
2 The major proline-rich region of Cbl was required for its phosphorylation by c-Abl, but not by a constitutively activated Abl mutant, suggesting Cbl activates c-Abl by engaging its SH3 domain. Proline Cbl proto-oncogene Homo sapiens