Title : Regulation of Cbl phosphorylation by the Abl tyrosine kinase and the Nck SH2/SH3 adaptor.

Pub. Date : 2001 Jul 5

PMID : 11494134






3 Functional Relationships(s)
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1 The major proline-rich region of Cbl was required for its phosphorylation by c-Abl, but not by a constitutively activated Abl mutant, suggesting Cbl activates c-Abl by engaging its SH3 domain. Proline ABL proto-oncogene 1, non-receptor tyrosine kinase Homo sapiens
2 The major proline-rich region of Cbl was required for its phosphorylation by c-Abl, but not by a constitutively activated Abl mutant, suggesting Cbl activates c-Abl by engaging its SH3 domain. Proline ABL proto-oncogene 1, non-receptor tyrosine kinase Homo sapiens
3 The major proline-rich region of Cbl was required for its phosphorylation by c-Abl, but not by a constitutively activated Abl mutant, suggesting Cbl activates c-Abl by engaging its SH3 domain. Proline ABL proto-oncogene 1, non-receptor tyrosine kinase Homo sapiens