Title : Crystal structure of the dimeric extracellular domain of human carbonic anhydrase XII, a bitopic membrane protein overexpressed in certain cancer tumor cells.

Pub. Date : 2001 Aug 14

PMID : 11493685






2 Functional Relationships(s)
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1 The structure of the CA XII-acetazolamide complex is also reported at 1.50-A resolution, and prospects for the design of CA XII-specific inhibitors of possible chemotherapeutic value are discussed. Acetazolamide carbonic anhydrase 12 Homo sapiens
2 The structure of the CA XII-acetazolamide complex is also reported at 1.50-A resolution, and prospects for the design of CA XII-specific inhibitors of possible chemotherapeutic value are discussed. Acetazolamide carbonic anhydrase 12 Homo sapiens