Title : Effects of formoterol and budesonide on GM-CSF and IL-8 secretion by triggered human bronchial epithelial cells.

Pub. Date : 2001 Jun

PMID : 11491146






3 Functional Relationships(s)
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1 Addition of formoterol (> or = 10(-10) M) reduced granulocyte macrophage-colony stimulating factor (GM-CSF) levels, as assessed by enzyme-linked immunosorbent assay, by 40-50% and increased interleukin (IL)-8 levels by approximately 50%. Formoterol Fumarate C-X-C motif chemokine ligand 8 Homo sapiens
2 In conclusion, the combination of budesonide and formoterol reduces the secretion of granulocyte macrophage-colony stimulating factor to basal levels and counteracts the capacity of formoterol alone to induce interleukin-8 production, modulations which may facilitate improved asthma control. Formoterol Fumarate C-X-C motif chemokine ligand 8 Homo sapiens
3 In conclusion, the combination of budesonide and formoterol reduces the secretion of granulocyte macrophage-colony stimulating factor to basal levels and counteracts the capacity of formoterol alone to induce interleukin-8 production, modulations which may facilitate improved asthma control. Formoterol Fumarate C-X-C motif chemokine ligand 8 Homo sapiens