Title : Distinct mechanisms of cell cycle arrest control the decision between differentiation and senescence in human neuroblastoma cells.

Pub. Date : 2001 Jul 31

PMID : 11481496






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Inhibition of DNA synthesis by RA is significantly more rapid in SH-F than in SH-N. SH-F, which expresses basal amounts of p16(INK4A), responds to RA with elevation of p18(INK4C), marked down-regulation of cyclin D1, and swift inhibition of cyclin D-dependent kinases (cdks). Tretinoin cyclin D1 Homo sapiens