Pub. Date : 2001 Apr 12
PMID : 11474544
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In rVR1-transfected HEK293 cells, acidic conditions enhanced the affinities of capsaicin and capsazepine at rVR1, but did not affect the potency of carbachol at endogenous muscarinic receptors. | Capsaicin | transient receptor potential cation channel, subfamily V, member 1 | Rattus norvegicus |
| 2 | In rVR1-transfected HEK293 cells, acidic conditions enhanced the affinities of capsaicin and capsazepine at rVR1, but did not affect the potency of carbachol at endogenous muscarinic receptors. | Capsaicin | transient receptor potential cation channel, subfamily V, member 1 | Rattus norvegicus |
| 3 | In conclusion, a decrease in pH (to 6.9 and 6.3) enhances the affinity of capsaicin at rVR1, but inhibits sensory neurotransmission in the rat mesenteric arterial bed. | Capsaicin | transient receptor potential cation channel, subfamily V, member 1 | Rattus norvegicus |