Title : Endothelin mediates some of the renal actions of acutely administered angiotensin II.

Pub. Date : 2001 Jul

PMID : 11463769






2 Functional Relationships(s)
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1 In the presence of bosentan, pressor and renal vasoconstrictor responses to low-dose angiotensin II were blunted (P<0.02 and P<0.01, respectively), and the results with BQ-123 were similar. Bosentan angiotensinogen Rattus norvegicus
2 In contrast, high-dose angiotensin II caused natriuretic and diuretic effects that were completely prevented by bosentan. Bosentan angiotensinogen Rattus norvegicus