Title : Modulation of the serological response to meningococcal polysaccharides by cytokines.

Pub. Date : 2001 Jul 20

PMID : 11457545






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 IL-2 increased significantly the IgG antibody response to conjugates of A and C polysaccharides with diphtheria mutant protein but exerted a minimal effect on the IgG response to B polysaccharide complexed with aluminium hydroxide and outer membrane proteins. Polysaccharides interleukin 2 Mus musculus
2 IL-2 increased significantly the IgG antibody response to conjugates of A and C polysaccharides with diphtheria mutant protein but exerted a minimal effect on the IgG response to B polysaccharide complexed with aluminium hydroxide and outer membrane proteins. Polysaccharides interleukin 2 Mus musculus
3 The stimulatory effect of IL-2 on the antibody responses to the polysaccharide antigens was not mediated by T-cells as similar results were obtained in athymic (nu/nu) and thymocompetent (nu/+) mice. Polysaccharides interleukin 2 Mus musculus