Title : Identification of cytochrome P-450 isoforms responsible for cis-tramadol metabolism in human liver microsomes.

Pub. Date : 2001 Aug

PMID : 11454734






1 Functional Relationships(s)
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1 Tramadol metabolism in human liver microsomes to M1 and M2 was markedly inhibited by the CYP2D6 inhibitor quinidine and the CYP3A4 inhibitor troleandomycin, respectively. Troleandomycin cytochrome P450 family 3 subfamily A member 4 Homo sapiens