Pub. Date : 2001
PMID : 11452979
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Inhibitors of kynurenine 3-hydroxylase have previously been used to increase endogenous levels of kynurenic acid, an excitatory amino acid receptor antagonist. | Kynurenic Acid | kynurenine 3-monooxygenase | Rattus norvegicus |
| 2 | The results of the present study show that a moderate increase in endogenous kynurenic acid levels produces significant actions on the tonic glutamatergic control of the firing pattern of nigral DA neurons, and implicate kynurenine 3-hydroxylase inhibitors as novel antiparkinsonian agents. | Kynurenic Acid | kynurenine 3-monooxygenase | Rattus norvegicus |