Title : Modulation of cell-substrate adhesion by arachidonic acid: lipoxygenase regulates cell spreading and ERK1/2-inducible cyclooxygenase regulates cell migration in NIH-3T3 fibroblasts.

Pub. Date : 2001 Jul

PMID : 11451994






1 Functional Relationships(s)
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1 An initial transient arachidonate release occurs during cell attachment to fibronectin, and is sufficient to signal the cell spreading stage after its oxidation by 5-lipoxygenase to leukotrienes. Leukotrienes arachidonate 5-lipoxygenase Mus musculus