Title : IL-6 inhibits the tolerogenic function of CD8 alpha+ dendritic cells expressing indoleamine 2,3-dioxygenase.

Pub. Date : 2001 Jul 15

PMID : 11441074






1 Functional Relationships(s)
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1 The activity of IL-6 includes down-regulation of IFN-gammaR expression in the CD8(+) DC subset and correlates to a reduced ability of these cells to metabolize tryptophan and initiate T cell apoptosis in vitro. Tryptophan interleukin 6 Mus musculus