Title : Detection of the protein-protein interaction between cyclic AMP receptor protein and RNA polymerase, by (13)C-carbonyl NMR.

Pub. Date : 2001 Jul

PMID : 11432780






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Upon the binding of cyclic AMP, CRP is allosterically activated, binds to target DNA sites, and interacts with RNA polymerase. Cyclic AMP C-reactive protein Homo sapiens
2 The result of (13)C-carbonyl NMR experiment on [(13)C"-Met]-CRP in the presence of both cyclic AMP and RNA polymerase alpha subunit showed that the two proteins interact with each other in solution in the absence of DNA via the region around the residues from Met 157 to Met 163 in CRP. Cyclic AMP C-reactive protein Homo sapiens
3 The result of (13)C-carbonyl NMR experiment on [(13)C"-Met]-CRP in the presence of both cyclic AMP and RNA polymerase alpha subunit showed that the two proteins interact with each other in solution in the absence of DNA via the region around the residues from Met 157 to Met 163 in CRP. Cyclic AMP C-reactive protein Homo sapiens