Title : In vitro effects of E3040, a dual inhibitor of 5-lipoxygenase and thromboxane A(2) synthetase, on eicosanoid production.

Pub. Date : 2001 Jun 22

PMID : 11430933






1 Functional Relationships(s)
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1 Sulfasalazine and 5-aminosalicylic acid, therapeutic drugs for inflammatory bowel disease, inhibited 5-lipoxygenase activity with an IC(50) of 293 and 970 microM, respectively. Mesalamine arachidonate 5-lipoxygenase Homo sapiens