Pub. Date : 2001 Jun
PMID : 11422371
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | To identify the transporter that could be involved in the efflux of RH-5992, the role of three ATP binding cassette transporters, Pdr5p, Snq2p and Ycf1p, has been studied using transporter-deletion mutants of yeast Saccharomyces cerevisiae. | Rhodium | ATP-binding cassette multidrug transporter PDR5 | Saccharomyces cerevisiae S288C |
| 2 | The mutants with the PDR5 deletion can also selectively accumulate [14C]RH-0345 and [14C]RH-2485, but not [14C]RH-5849, indicating that these three compounds share the same transporter Pdr5p for efflux. | Rhodium | ATP-binding cassette multidrug transporter PDR5 | Saccharomyces cerevisiae S288C |
| 3 | The mutants with the PDR5 deletion can also selectively accumulate [14C]RH-0345 and [14C]RH-2485, but not [14C]RH-5849, indicating that these three compounds share the same transporter Pdr5p for efflux. | Rhodium | ATP-binding cassette multidrug transporter PDR5 | Saccharomyces cerevisiae S288C |
| 4 | The mutants with the PDR5 deletion can also selectively accumulate [14C]RH-0345 and [14C]RH-2485, but not [14C]RH-5849, indicating that these three compounds share the same transporter Pdr5p for efflux. | Rhodium | ATP-binding cassette multidrug transporter PDR5 | Saccharomyces cerevisiae S288C |