Pub. Date : 2001 Aug 17
PMID : 11402046
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Intracellular Ca2+ and Zn2+ levels regulate the alternative cell density-dependent secretion of S100B in human glioblastoma cells. | Zinc | S100 calcium binding protein B | Homo sapiens |
| 2 | In contrast, relocation of S100B seemed to be negatively dependent on Zn(2+) levels. | Zinc | S100 calcium binding protein B | Homo sapiens |
| 3 | Treatment of cells with TPEN (N,N,N",N"-tetrakis(2-pyridylmethyl)ethylenediamine), a Zn(2+)-binding drug, resulted in a dramatic redistribution and translocation of S100B. | Zinc | S100 calcium binding protein B | Homo sapiens |
| 4 | However, an increase in Ca(2+) levels, and even more so, a decrease in Zn(2+) concentration, reactivated secretion of S100B. | Zinc | S100 calcium binding protein B | Homo sapiens |