Title : Ionomycin causes activation of p38 and p42/44 mitogen-activated protein kinases in human neutrophils.

Pub. Date : 2001 Jul

PMID : 11401859






1 Functional Relationships(s)
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1 SB-203580, a p38 MAP kinase antagonist, inhibited ionomycin-induced activation of the oxidase (68 +/- 8%, P < 0.05) and tyrosine phosphorylation of 105- and 72-kDa proteins; conversely, PD-98059, an inhibitor of MAP/extracellular signal-related kinase 1, had no effect. Ionomycin mitogen-activated protein kinase 3 Homo sapiens