Pub. Date : 2001 Apr
PMID : 11392610
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | RESULTS: A23187 and thapsigargin caused a dose- and time-dependent accumulation of IL-8 mRNA and protein production which was dependent on the release of Ca2+ from intracellular stores. | Calcimycin | C-X-C motif chemokine ligand 8 | Homo sapiens |
| 2 | FK506, a specific inhibitor of calcineurin, inhibited A23187- and thapsigargin-induced IL-8 mRNA expression in a dose dependent manner. | Calcimycin | C-X-C motif chemokine ligand 8 | Homo sapiens |
| 3 | Reporter gene studies and actinomycin D chase experiments showed that A23187 and thapsigargin enhanced IL-8 gene transcription and stabilized IL-8 mRNA transcripts, respectively. | Calcimycin | C-X-C motif chemokine ligand 8 | Homo sapiens |
| 4 | Reporter gene studies and actinomycin D chase experiments showed that A23187 and thapsigargin enhanced IL-8 gene transcription and stabilized IL-8 mRNA transcripts, respectively. | Calcimycin | C-X-C motif chemokine ligand 8 | Homo sapiens |