Title : Protein kinase C-catalyzed phosphorylation of an inhibitory phosphoprotein of myosin phosphatase is involved in human platelet secretion.

Pub. Date : 2001 Jun 15

PMID : 11389019






1 Functional Relationships(s)
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1 Treatment of intact platelets with thrombin or the stable thromboxane A(2) analog STA(2) resulted in increased phosphorylation of both CPI and MBS at Thr-696, whereas phorbol myristate acetate (PMA) and the Ca(++) ionophore ionomycin only induced CPI phosphorylation. Ionomycin coagulation factor II, thrombin Homo sapiens