Title : The death substrate Gas2 binds m-calpain and increases susceptibility to p53-dependent apoptosis.

Pub. Date : 2001 Jun 1

PMID : 11387205






1 Functional Relationships(s)
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1 Here we provide evidence that overexpression of Gas2 efficiently increases cell susceptibility to apoptosis following UV irradiation, etoposide and methyl methanesulfonate treatments, and that these effects are dependent on increased p53 stability and transcription activity. Methyl Methanesulfonate tumor protein p53 Homo sapiens