Title : Crk family adaptor proteins trans-activate c-Abl kinase.

Pub. Date : 2001 May

PMID : 11380621






3 Functional Relationships(s)
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1 The interaction of the amino-terminal Src-homology (SH) 3 domain of c-Crk and the proline-rich motifs of c-Abl is an essential step for the phosphorylation of c-Crk by c-Abl, as well as the activation of c-Abl by c-Crk. Proline ABL proto-oncogene 1, non-receptor tyrosine kinase Homo sapiens
2 The interaction of the amino-terminal Src-homology (SH) 3 domain of c-Crk and the proline-rich motifs of c-Abl is an essential step for the phosphorylation of c-Crk by c-Abl, as well as the activation of c-Abl by c-Crk. Proline ABL proto-oncogene 1, non-receptor tyrosine kinase Homo sapiens
3 The interaction of the amino-terminal Src-homology (SH) 3 domain of c-Crk and the proline-rich motifs of c-Abl is an essential step for the phosphorylation of c-Crk by c-Abl, as well as the activation of c-Abl by c-Crk. Proline ABL proto-oncogene 1, non-receptor tyrosine kinase Homo sapiens