Title : Establishment of the transformants expressing human cytochrome P450 subtypes in HepG2, and their applications on drug metabolism and toxicology.

Pub. Date : 2001 Jun

PMID : 11377097






1 Functional Relationships(s)
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1 These results show the metabolic activation of APAP, CPA and BA by the specific CYP subtypes expressed in the transformants and demonstrate the usefulness of these transformants for in vitro metabolic and toxicological studies in human liver. Acetaminophen cytochrome P450 family 4 subfamily F member 3 Homo sapiens