Title : Blockade of AMPA receptors and volatile anesthetics: reduced anesthetic requirements in GluR2 null mutant mice for loss of the righting reflex and antinociception but not minimum alveolar concentration.

Pub. Date : 2001 Mar

PMID : 11374610






1 Functional Relationships(s)
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1 Paradoxically, GluR2 null mutant (-/-) mice are more sensitive to barbiturate-induced loss of the righting reflex (LORR) compared with wild-type (+/+) littermates. barbituric acid glutamate receptor, ionotropic, AMPA2 (alpha 2) Mus musculus