Title : Serotonin 5-HT1 receptors potentiate histamine and thrombin stimulated prostaglandin synthesis in endothelial cells.

Pub. Date : 2001 May

PMID : 11372689






4 Functional Relationships(s)
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1 Serotonin 5-HT1 receptors potentiate histamine and thrombin stimulated prostaglandin synthesis in endothelial cells. Prostaglandins coagulation factor II, thrombin Homo sapiens
2 However, 5-CT potentiated the histamine and thrombin stimulated increases in prostaglandins released by HAEC. Prostaglandins coagulation factor II, thrombin Homo sapiens
3 The ability of 5-CT to potentiate prostaglandin production was correlated with its ability to potentiate the histamine and thrombin mediated mobilization of arachidonic acid. Prostaglandins coagulation factor II, thrombin Homo sapiens
4 These results demonstrate that the ability of 5-HT1 receptors to stimulate prostaglandin production in endothelial cells is activated by histamine and thrombin. Prostaglandins coagulation factor II, thrombin Homo sapiens