Title : Effects of FK506 and other immunosuppressive anti-rheumatic agents on T cell activation mediated IL-6 and IgM production in vitro.

Pub. Date : 2001 Apr

PMID : 11357886






4 Functional Relationships(s)
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1 Effects of FK506 and other immunosuppressive anti-rheumatic agents on T cell activation mediated IL-6 and IgM production in vitro. Tacrolimus interleukin 6 Homo sapiens
2 FK506 potently inhibited IL-6 production from PBMC stimulated with anti-CD3 and anti-CD28 monoclonal antibody (anti-CD3/CD28). Tacrolimus interleukin 6 Homo sapiens
3 The present study suggests that FK506 is the most effective among the four agents for the suppression of IL-6 production and IL-6-mediated autoantibody production in T cell activation related autoimmune diseases such as RA. Tacrolimus interleukin 6 Homo sapiens
4 The present study suggests that FK506 is the most effective among the four agents for the suppression of IL-6 production and IL-6-mediated autoantibody production in T cell activation related autoimmune diseases such as RA. Tacrolimus interleukin 6 Homo sapiens